System design study of a VLEO satellite platform using the IRS RF helicon-based plasma thruster

To achieve a feasible lifetime of several years, most satellites are deployed in orbits higher than 400 km. Drag of residual atmosphere causes a slow orbit decay, resulting in the deorbit of the spacecraft. However, e.g. optical instruments or communication devices would significantly benefit from lower altitudes in the range of 150–250 km. A solution to achieve this could be the application of atmosphere-breathing electric propulsion (ABEP), where the residual atmosphere is used to generate continuous thrust that compensates the drag.Within the EU-funded DISCOVERER project, the Institute of Space Systems (IRS) developed an electrode-less RF Helicon-based Plasma Thruster (IPT) suitable for such applications. Ignition and preliminary discharge characterizations of the IPT have been carried out at IRS facilities, using argon, nitrogen and oxygen. To further characterize the plasma plume, a torsional pendulum has been designed to determine the (local) momentum flux in the plasma jet, as well as a three-axis magnetic B-dot probe to carry out time-varying magnetic field measurements. Various intake designs were investigated, opening the possibility to conduct studies on potential satellite platforms within the frame of the ESA-funded project RAM-CLEP.A design study for an Earth Observation and Telecommunication satellite operating at 150–250 km with an extended mission lifetime is currently being carried out. The first system assessment focused on the comparison of different spacecraft configurations (“slender body” and “flat body”) and intake designs (specular or diffuse) with regard to overall drag and ABEP performance requirements.In this contribution, the design approaches for the current thruster and the diagnostic methods are depicted. Moreover, the current status of the system assessment is presented. Upcoming experimental studies of the ABEP system e.g. within the ESA-project RAM-CLEP and additional activities planned on system assessment are outlined.<br/

What does the takeoff leg really do?

Amine transaminases (ATAs) are powerful enzymes for the stereospecific production of chiral amines. However, the synthesis of amines incorporating more than one stereocenter is still a challenge. We developed a cascade synthesis to access optically active 3-alkyl-substituted chiral amines by combining two asymmetric synthesis steps catalyzed by an enoate reductase and ATAs. The ATA wild type from Vibrio fluvialis showed only modest enantioselectivity (14 % de) in the amination of (S)-3-methylcyclohexanone, the product of the enoate-reductase-catalyzed reaction step. However, by protein engineering we created two variants with substantially improved diastereoselectivities: variant Leu56Val exhibited a higher R selectivity (66 % de) whereas the Leu56Ile substitution caused a switch in enantiopreference to furnish the S-configured diastereomer (70 % de). Addition of 30 % DMSO further improved the selectivity and facilitated the synthesis of (1R,3S)-1-amino-3-methylcyclohexane with 89 % de at 87 % conversion

NewProt - a protein engineering portal

Contains fulltext : 176900.pdf (publisher's version ) (Closed access)The NewProt protein engineering portal is a one-stop-shop for in silico protein engineering. It gives access to a large number of servers that compute a wide variety of protein structure characteristics supporting work on the modification of proteins through the introduction of (multiple) point mutations. The results can be inspected through multiple visualizers. The HOPE software is included to indicate mutations with possible undesired side effects. The Hotspot Wizard software is embedded for the design of mutations that modify a proteins' activity, specificity, or stability. The NewProt portal is freely accessible at http://newprot.cmbi.umcn.nl/ and http://newprot.fluidops.net/